Employee Benefits

Grapefruit and Some Prescription Drugs Don’t Mix

grapefruit reactions

If you regularly consume grapefruit or grapefruit juice, make sure you share this information with your doctor in advance of taking a prescribed medication.

According to Canadian researchers, there are 85 drugs that may interact negatively with grapefruit or grapefruit juice – even when consumed in small amounts. The side effects may be serious, including sudden death, acute kidney or respiratory failure and gastrointestinal bleeding. These drugs are all taken orally and include blood pressure drugs, cancer treatments, some cholesterol absorption inhibitors and antibiotics, such as erythromycin.

Scientists also have discovered that grapefruit, along with limes and Seville oranges, contain furanocoumarins, a chemical compound that causes the body to absorb medications at a higher rate – similar to taking several doses of the drug at one time.

Learn more about the side effects of combining grapefruit with some prescription drugs:

More New Drugs a Bad Fit With Grapefruit, Study Finds

Drinking grapefruit juice with some medications can be deadly, study warns

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